Complex Growth of Benzamide Form I: Effect of Additives, Solution Flow, and Surface Rugosity.

ABSTRACT: Understanding crystal growth kinetics is of great importance for the development and manufacturing of crystalline molecular materials. In this work, the impact of additives on the growth kinetics of benzamide form I (BZM-I) crystals has been studied. Using our newly developed crystal growth setup for the measurement of facet-specific crystal growth rates under flow, BZM-I growth rates were measured in the presence of various additives previously reported to induce morphological changes. The additives did not have a significant impact on the growth rates of BZM-I at low concentrations. By comparison to other systems, these additives could not be described as "effective" since BZM-I showed a high tolerance of the additives' presence during growth, which may be a consequence of the type of gr

SUBMITTER: Offiler CA 

PROVIDER: S-EPMC9542702 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature