Dataset Information

Preoperative imaging in primary hyperparathyroidism: Are ¹¹ C-Choline PET/CT and ^99m Tc-MIBI/¹²³ Iodide subtraction SPECT/CT interchangeable or do they supplement each other?

ABSTRACT:

Objective

Preoperative location of hyperfunctioning parathyroid glands (HPGs) is vital when planning minimally invasive surgery in patients with primary hyperparathyroidism (PHPT). Dual-isotope subtraction scintigraphy with ^99m Tc-MIBI/¹²³ Iodide using SPECT/CT and planar pinhole imaging (Di-SPECT) has shown high sensitivity, but is challenged by high radiation dose, time consumption and cost. ¹¹ C-Choline PET/CT (faster with a lower radiation dose) is non-inferior to Di-SPECT. We aim to clarify to what extent the two are interchangeable and how often there are discrepancies.

Design

This is a prospective, GCP-controlled cohort study.

Patients and measurements

One hundred patients diagnosed with PHPT were included and underwent both ima

SUBMITTER: Christensen JW

PROVIDER: S-EPMC9542777 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature

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Dataset Information

Preoperative imaging in primary hyperparathyroidism: Are ¹¹ C-Choline PET/CT and ^99m Tc-MIBI/¹²³ Iodide subtraction SPECT/CT interchangeable or do they supplement each other?

Objective

Design

Patients and measurements

OmicsDI is part of the ELIXIR infrastructure

Tweets

Dataset Information

Preoperative imaging in primary hyperparathyroidism: Are 11 C-Choline PET/CT and 99m Tc-MIBI/123 Iodide subtraction SPECT/CT interchangeable or do they supplement each other?

Objective

Design

Patients and measurements

OmicsDI is part of the ELIXIR infrastructure

Tweets

Preoperative imaging in primary hyperparathyroidism: Are ¹¹ C-Choline PET/CT and ^99m Tc-MIBI/¹²³ Iodide subtraction SPECT/CT interchangeable or do they supplement each other?