Venous thromboembolic events in glioblastoma patients: An epidemiological study.

ABSTRACT:

Background and purpose

Venous thromboembolic events (VTEs) are a major complication in cancer patients, and therefore, also in brain cancer patients, anticoagulants are considered appropriate in the treatment of VTEs.

Methods

Frequency, risk factors, and treatment of VTEs, as well as associated complications, were assessed in a population-based cohort of glioblastoma patients in the Canton of Zurich, Switzerland. Correlations between clinical data and survival were retrospectively analyzed using the log-rank test and Cox regression models.

Results

Four hundred fourteen glioblastoma patients with isocitrate dehydrogenase wild-type status were identified. VTEs were documented in 65 patients (15.7%). Median time from tumor diagnosis to the occurrence of a VTE was 1.8 mon

SUBMITTER: Eisele A 

PROVIDER: S-EPMC9543144 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature