Altered motivation of effortful decision-making for self and others in subthreshold depression.

ABSTRACT:

Background

Amotivation is a typical feature in major depressive disorders and refers to individuals exhibiting reduced willingness to exert effort for rewards. However, the motivation pattern when deciding whether to exert effort for self versus others in people with depression remains unclear.

Methods

We conducted a functional magnetic resonance imaging study and employed an adapted Effort-Expenditure for Rewards Task in subthreshold depressive (SD) participants (n = 33) and healthy controls (HC) (n = 32). This required participants to choose between a fixed low-effort/low-reward and a variable high-effort/high-reward option, and then immediately exert effort to obtain corresponding rewards for themselves or for unfamiliar people.

Results

Compared with the HC group,

SUBMITTER: Bi R 

PROVIDER: S-EPMC9543190 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature