Immediate birth for women between 34 and 37 weeks of gestation with prolonged preterm prelabour rupture of membranes and detection of vaginal or urine group B streptococcus: an economic evaluation.

ABSTRACT:

Objective

What are the costs, benefits and harms of immediate birth compared with expectant management in women with prolonged preterm prelabour rupture of membranes (PPROM) at 34⁺⁰ -36⁺⁶  weeks of gestation and detection of vaginal or urine group B streptococcus (GBS)?

Design

Mathematical decision model comprising three independent decision trees.

Setting

UK National Health Service (NHS) and personal social services perspective.

Population

Women testing positive for GBS with PPROM at 34⁺⁰ -36⁺⁶  weeks of gestation.

Methods

The model estimates lifetime costs and quality-adjusted life years (QALYs) using evidence from randomised trials, UK NHS data sources and further observational studies. Simulated events incl

SUBMITTER: Dietz J 

PROVIDER: S-EPMC9543209 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature