The effect of a mixed cannabidiol and cannabidiolic acid based oil on client-owned dogs with atopic dermatitis.

ABSTRACT:

Background

Cannabidiol (CBD) and cannabidiolic acid (CBDA) are reported to have antinociceptive, immunomodulatory and anti-inflammatory actions.

Objectives

To determine if CBD/CBDA is an effective therapy for canine atopic dermatitis (cAD).

Animals

Thirty-two privately owned dogs with cAD.

Materials and methods

Prospective, randomised, double-blinded, placebo-controlled study. Concurrent therapies were allowed if remained unchanged. Dogs were randomly assigned to receive either 2 mg/kg of an equal mix of CBD/CBDA (n = 17) or placebo for 4 weeks. On Day (D)0, D14 and D28, Canine Atopic Dermatitis Extent and Severity Index, 4th iteration (CADESI-04) and pruritus Visual Analog Scale (pVAS) scores were determined by investigators and owners, respectively. Complete

SUBMITTER: Loewinger M 

PROVIDER: S-EPMC9543248 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature