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Acetylsalicylic acid use is associated with improved survival in bacteremic pneumococcal pneumonia: A long-term nationwide study.


ABSTRACT:

Background

Pneumonia is commonly caused by Streptococcus pneumoniae (pneumococcus) and associated with subsequent cardiovascular complications and increased mortality. Potential short-term survival benefits conferred by acetylsalicylic acid (ASA) use in pneumonia remain controversial, and long-term outcomes have not been studied.

Objectives

To evaluate the association between ASA use and survival for up to 1 year following bacteremic pneumococcal pneumonia.

Methods

All bacteremic pneumococcal episodes in Iceland from 1975 to 2019 were reviewed. The study cohort consisted of individuals at least 18 years of age with symptoms and imaging results consistent with pneumonia. Differences in survival were assessed at 30 days, 90 days and 1 year using propensity score weighti

SUBMITTER: Rognvaldsson KG 

PROVIDER: S-EPMC9543431 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature