Fraction of inspired oxygen during general anesthesia for non-cardiac surgery: Systematic review and meta-analysis.

ABSTRACT:

Background

Controversy exists regarding the effects of a high versus a low intraoperative fraction of inspired oxygen (FiO₂ ) in adults undergoing general anesthesia. This systematic review and meta-analysis investigated the effect of a high versus a low FiO₂ on postoperative outcomes.

Methods

PubMed and Embase were searched on March 22, 2022 for randomized clinical trials investigating the effect of different FiO₂ levels in adults undergoing general anesthesia for non-cardiac surgery. Two investigators independently reviewed studies for relevance, extracted data, and assessed risk of bias. Meta-analyses were performed for relevant outcomes, and potential effect measure modification was assessed in subgroup analyses and meta-regression. The e

SUBMITTER: Hoybye M 

PROVIDER: S-EPMC9543529 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature