Evaluation of Monoexponential, Stretched-Exponential and Intravoxel Incoherent Motion MRI Diffusion Models in Early Response Monitoring to Neoadjuvant Chemotherapy in Patients With Breast Cancer-A Preliminary Study.

ABSTRACT:

Background

There has been a growing interest in exploring the applications of stretched-exponential (SEM) and intravoxel incoherent motion (IVIM) models of diffusion-weighted imaging (DWI) in breast imaging, with the focus on differentiation of breast lesions. However, the use of SEM and IVIM models to predict early response to neoadjuvant chemotherapy (NACT) has received less attention.

Purpose

To investigate the value of monoexponential, SEM, and IVIM models to predict early response to NACT in patients with primary breast cancer.

Study type

Prospective.

Population

Thirty-seven patients with primary breast cancer (aged 46 ± 11 years) due to undergo NACT.

Field strength/sequences

A 1.5-T MR scanner, T₁ -weighted three-dimensional spoiled grad

SUBMITTER: Almutlaq ZM 

PROVIDER: S-EPMC9543625 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature