A meta-analytic investigation of grey matter differences in anorexia nervosa and autism spectrum disorder.

ABSTRACT: Recent research reports Anorexia Nervosa (AN) to be highly dependent upon neurobiological function. Some behaviours, particularly concerning food selectivity are found in populations with both Autism Spectrum Disorder (ASD) and AN, and there is a proportionally elevated number of anorexic patients exhibiting symptoms of ASD. We performed a systematic review of structural MRI literature with the aim of identifying common structural neural correlates common to both AN and ASD. Across 46 ASD publications, a meta-analysis of volumetric differences between ASD and healthy controls revealed no consistently affected brain regions. Meta-analysis of 23 AN publications revealed increased volume within the orbitofrontal cortex and medial temporal lobe, and adult-only AN literature revealed difference

SUBMITTER: Sader M 

PROVIDER: S-EPMC9543727 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature