Optimizing laboratory-based surveillance networks for monitoring multi-genotype or multi-serotype infections.

ABSTRACT: With the aid of laboratory typing techniques, infectious disease surveillance networks have the opportunity to obtain powerful information on the emergence, circulation, and evolution of multiple genotypes, serotypes or other subtypes of pathogens, informing understanding of transmission dynamics and strategies for prevention and control. The volume of typing performed on clinical isolates is typically limited by its ability to inform clinical care, cost and logistical constraints, especially in comparison with the capacity to monitor clinical reports of disease occurrence, which remains the most widespread form of public health surveillance. Viewing clinical disease reports as arising from a latent mixture of pathogen subtypes, laboratory typing of a subset of clinical cases can provide i

SUBMITTER: Cheng Q 

PROVIDER: S-EPMC9543988 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature