Risk factors for administration of additional reversal following neuromuscular blockade with rocuronium in children: A retrospective case-control study.

ABSTRACT:

Background

The prevalence and risk factors for residual neuromuscular blockade in children remain poorly characterized. We hypothesize that specific patient and anesthetic risk factors may be associated with the administration of additional reversal in children following initial reversal of rocuronium with neostigmine.

Methods

Our electronic health record was queried for patients <18 years of age who received rocuronium and reversal with neostigmine from 2017 through 2020. Patients receiving other nondepolarizing neuromuscular blocking drugs were excluded. The outcome of interest was defined as the administration of additional neostigmine or sugammadex following primary reversal with neostigmine. Time between the last dose of rocuronium and initial dose of neostigmine, and t

SUBMITTER: Vishneski SR 

PROVIDER: S-EPMC9544061 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature