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Dataset Information

Risk factors for local atypical fibroxanthoma recurrence and progression to pleomorphic dermal sarcoma: A meta-analysis of individualized participant data.


ABSTRACT:

Background

Risk factors for local atypical fibroxanthoma (AFX) recurrence and progression to pleomorphic dermal sarcoma (PDS) have not previously been identified.

Objective

To identify risk factors and provide follow-up suggestions for local AFX recurrence and progression to PDS.

Methods and materials

A literature search was performed in the PubMed, EMBASE, and Cochrane databases. The PRISMA and MOOSE guidelines were followed. The risks of local AFX recurrence and progression to PDS were presented as Kaplan-Meier plots and risk factors were presented as hazard ratios (HRs) calculated with univariate and multivariate Cox regression.

Results

Five hundred and ninety-eight patients with AFX from 14 studies were included. Age >74 years and male sex significantly inc

SUBMITTER: Orholt M 

PROVIDER: S-EPMC9544245 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature

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