Metabolite-cycled echo-planar spectroscopic imaging of the human heart.

ABSTRACT:

Purpose

Spectroscopic imaging could provide insights into regional cardiac triglyceride variations, but is hampered by relatively long scan times. It is proposed to synergistically combine echo-planar spectroscopic imaging (EPSI) with motion-adapted gating, weighted acquisition and metabolite cycling to reduce scan times to less than 10 min while preserving spatial-spectral quality. The method is compared to single-voxel measurements and to metabolite-cycled EPSI with conventional acquisition for assessing triglyceride-to-water (TG/W) ratios in the human heart.

Methods

Measurements were performed on 10 healthy volunteers using a clinical 1.5T system. EPSI data was acquired both without and with motion-adapted gating in combination with weighted acquisition to assess TG/W rat

SUBMITTER: Peereboom SM 

PROVIDER: S-EPMC9544353 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature