Detection of Intramyocardial Iron in Patients Following ST-Elevation Myocardial Infarction Using Cardiac Diffusion Tensor Imaging.

ABSTRACT:

Background

Intramyocardial hemorrhage (IMH) following ST-elevation myocardial infarction (STEMI) is associated with poor prognosis. In cardiac magnetic resonance (MR), T2* mapping is the reference standard for detecting IMH while cardiac diffusion tensor imaging (cDTI) can characterize myocardial architecture via fractional anisotropy (FA) and mean diffusivity (MD) of water molecules. The value of cDTI in the detection of IMH is not currently known.

Hypothesis

cDTI can detect IMH post-STEMI.

Study type

Prospective.

Subjects

A total of 50 patients (20% female) scanned at 1-week (V1) and 3-month (V2) post-STEMI.

Field strength/sequence

A 3.0 T; inversion-recovery T1-weighted-imaging, multigradient-echo T2* mapping, spin-echo cDTI.

Assessment

T2* map

SUBMITTER: Das A 

PROVIDER: S-EPMC9544509 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature