Associations between pre- and postnatal antibiotic exposures and early allergic outcomes: A population-based birth cohort study.

ABSTRACT:

Background

Early life antibiotic treatment is one likely exposure influencing allergy risk. The objective was to investigate associations between pre- and postnatal antibiotic exposures and the development of allergic manifestations until age 18 months.

Methods

We included 1387 mother-child dyads from the prospective, population-based NorthPop birth cohort study. Data on antibiotic exposures in pregnancy and childhood were collected by web-based questionnaires. Until the child turned 18 months old, parents (n = 1219) reported symptoms of wheeze, eczema, and physician-diagnosed asthma; parents (n = 1025) reported physician-diagnosed food allergy. At age 18 months, serum immunoglobulin E levels to inhalant (Phadiatop) and food (Food mix fx5) allergens were determined. Associat

SUBMITTER: Kelderer F 

PROVIDER: S-EPMC9544930 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature