Effect of number of diffusion-encoding directions in diffusion metrics of 5-year-olds using tract-based spatial statistical analysis.

ABSTRACT: Methodological aspects and effects of different imaging parameters on DTI (diffusion tensor imaging) results and their reproducibility have been recently studied comprehensively in adult populations. Although MR imaging of children's brains has become common, less interest has been focussed on researching whether adult-based optimised parameters and pre-processing protocols can be reliably applied to paediatric populations. Furthermore, DTI scalar values of preschool aged children are rarely reported. We gathered a DTI dataset from 5-year-old children (N = 49) to study the effect of the number of diffusion-encoding directions on the reliability of resultant scalar values with TBSS (tract-based spatial statistics) method. Additionally, the potential effect of within-scan head motion on DTI

SUBMITTER: Kumpulainen V 

PROVIDER: S-EPMC9545012 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature