Is early exposure to cannabis associated with bipolar disorder? Results from a Finnish birth cohort study.

ABSTRACT:

Background and aims

There are few longitudinal studies assessing the association of cannabis use and subsequent onset of bipolar disorder. We aimed to measure the association between early cannabis exposure and subsequent bipolar disorder.

Design, setting and participants

Observational study linking a sample from the northern Finland birth cohort 1986 (n = 6325) to nation-wide register data to examine the association of life-time cannabis exposure at age 15/16 years and subsequent bipolar disorder until age 33 (until the end of 2018); 6325 individuals (48.8% males) were included in the analysis.

Measurements

Cannabis exposure was measured via self-report. Bipolar disorder was measured via bipolar disorder-related diagnostic codes (ICD-10: F30.xx, F31.xx) collected fro

SUBMITTER: Denissoff A 

PROVIDER: S-EPMC9545505 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature