Tracheostomy is associated with increased survival in Multiple System Atrophy patients with stridor.

ABSTRACT:

Background and purpose

Stridor treatment in multiple system atrophy (MSA) mainly comprises tracheostomy or continuous positive airway pressure (CPAP), but guidelines for the use of these treatments are lacking. The aim of the study was to evaluate the predictive value of stridor treatment in an MSA cohort.

Methods

This is a retrospective and prospective monocentric cohort study including MSA patients evaluated at least once a year during the disease course. Stridor was video-polysomnography confirmed. The time of stridor treatment (CPAP or tracheostomy) and latency from stridor onset were collected. Survival and predictors of survival were calculated.

Results

A total of 182 (107 males, mean age at disease onset 57.3 ± 8.4 years) MSA patients were included in the study

SUBMITTER: Giannini G 

PROVIDER: S-EPMC9545543 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature