Cognitive subgroups and their longitudinal trajectories in bipolar disorder.

ABSTRACT:

Introduction

Cognitive functioning in bipolar disorder is heterogeneous with evidence for multiple subgroups. However, cognitive subgroup change patterns over time remains unknown. While prior work suggests minimal differences in cognitive functioning patterns over time between those with bipolar disorder and controls, group-based analyses may obscure unique subgroup-based changes.

Material and methods

Participants diagnosed with bipolar disorder (I, II, NOS; n = 568) and unaffected controls (n = 234) completed baseline, one- and five-year neuropsychological assessments. Data reduction techniques were used to limit the number of neuropsychological variables. Bipolar disorder participant baseline neuropsychological data were entered into hierarchical cluster analyses and resu

SUBMITTER: Ehrlich TJ 

PROVIDER: S-EPMC9545624 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature