Protein signalling in response to ex vivo dynamic contractions is independent of training status in rat skeletal muscle.

ABSTRACT:

New findings

What is the central question of this study? Are myofibre protein signalling responses to ex vivo dynamic contractions altered by accustomization to voluntary endurance training in rats? What is the main finding and its importance? In response to ex vivo dynamic muscle contractions, canonical myofibre protein signalling pertaining to metabolic transcriptional regulation, as well as translation initiation and elongation, was not influenced by prior accustomization to voluntary endurance training in rats. Accordingly, intrinsic myofibre protein signalling responses to standardized contractile activity may be independent of prior exercise training in rat skeletal muscle.

Abstract

Skeletal muscle training status may influence myofibre regulatory protein signalling in

SUBMITTER: Jakobsgaard JE 

PROVIDER: S-EPMC9545705 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature