Development of a Monte Carlo based robustness calculation and evaluation tool.

ABSTRACT:

Background

Evaluating plan robustness is a key step in radiotherapy.

Purpose

To develop a flexible Monte Carlo (MC)-based robustness calculation and evaluation tool to assess and quantify dosimetric robustness of intensity-modulated radiotherapy (IMRT) treatment plans by exploring the impact of systematic and random uncertainties resulting from patient setup, patient anatomy changes, and mechanical limitations of machine components.

Methods

The robustness tool consists of two parts: the first part includes automated MC dose calculation of multiple user-defined uncertainty scenarios to populate a robustness space. An uncertainty scenario is defined by a certain combination of uncertainties in patient setup, rigid intrafraction motion and in mechanical steering of the f

SUBMITTER: Loebner HA 

PROVIDER: S-EPMC9545707 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature