Critical update, systematic review, and meta-analysis of oral erythroplakia as an oral potentially malignant disorder.

ABSTRACT:

Background

Oral erythroplakia has been classically considered as the potentially malignant disorder with the highest rate of malignant development into squamous cell carcinoma. This critical systematic review and meta-analysis aim to estimate the malignant development rate of oral erythroplakia and identify the associated risk factors.

Methods

We performed a bibliographic search in PubMed, Scopus, Web of Science, Embase, and LILACS, with keywords "erythroplakia," "erythroplasia," "malignant transformation," "malignant development," "malignization," "carcinogenesis," "oral cancer," "oral squamous cell carcinoma," "mouth neoplasm," and "prognosis." Meta-analysis was conducted using a random-effects model.

Results

Ten observational studies with 441 patients met the inclu

SUBMITTER: Lorenzo-Pouso AI 

PROVIDER: S-EPMC9545979 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature