Harmonizing platelet function analyzer testing and reporting in a large laboratory network.

ABSTRACT:

Introduction

The platelet function analyzer (PFA) is a popular platelet function screening instrument, highly sensitive to von Willebrand disease (VWD) and to aspirin therapy, with moderate sensitivity to defects in platelet function and/or deficiencies in platelet number. There are two models, the original PFA-100 and the contemporary PFA-200. Normal reference ranges (NRRs) provided by the manufacturer are the same for both models, instead being based on the type of test cartridge, for which there are two main ones: collagen/epinephrine (C/Epi) and collagen/adenosine diphosphate (C/ADP).

Methods

Comparative evaluations of PFA testing and reporting in six different sites of a large pathology network, aiming to harmonize NRRs and test reporting across all network sites. A sep

SUBMITTER: Favaloro EJ 

PROVIDER: S-EPMC9545980 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature