Psychometric parameters of food allergy quality of life during an allergen immunotherapy trial.

ABSTRACT:

Background

The Food Allergy Quality of Life Questionnaire-Parent Form (FAQLQ-PF) is a commonly used patient-reported outcome measure in food allergy (FA) research. It was developed before FA treatment clinical trials were commonplace and is used as a secondary outcome measure in pivotal FA treatment trials. We examined the psychometric properties of the FAQLQ-PF and its relevance to children with peanut allergy engaged in an epicutaneous immunotherapy (EPIT) clinical trial.

Methods

Analysis was performed on 26 universally answered items of the FAQLQ-PF, from assessments undertaken during the phase 3 PEPITES study (baseline, Month 12), which examined the safety and efficacy of EPIT for children with peanut allergy aged 4-11 years. Item response theory (IRT) was used to assess

SUBMITTER: Lins de Holanda Coelho G 

PROVIDER: S-EPMC9546060 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature