Predicting organ functioning with and without blood transfusion in critically ill patients with anemia.

ABSTRACT:

Background

To develop a model for the prediction of the (most likely) effect of red blood cell (RBC) transfusion on subsequent organ functioning in nonbleeding critically ill patients with hemoglobin concentrations between 6 and 9 g/dL.

Study design and methods

We conducted a retrospective cohort study using electronic health care data of nonbleeding patients admitted between November 2004 and May 2016 at the intensive care unit (ICU) of the Leiden University Medical Center, The Netherlands. We analyzed the associations between transfusion (yes/no) and next-day SOFA scores (Sequential Organ Failure Assessment-as a measure for organ functioning) for all observed combinations of hemoglobin values (between 6 and 9 g/dL) and concurrent clinical variables.

Results

Data of

SUBMITTER: Kranenburg FJ 

PROVIDER: S-EPMC9546226 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature