Cardiovascular outcomes in patients with left atrial enlargement undergoing transcatheter aortic valve implantation.

ABSTRACT:

Background

Increased left ventricular afterload resulting from severe aortic stenosis (AS) leads to progressive cardiac remodeling. Left atrial enlargement (LAE) is an early manifestation in a series of maladaptive changes and may affect clinical outcomes after valvular replacement therapy. The aim of this study is to determine the impact of LAE on clinical outcomes in symptomatic patients with severe AS undergoing transcatheter aortic valve implantation (TAVI).

Methods

In a prospective single-center TAVI registry, we analyzed LA dimensions measured by echocardiography before intervention. Patients with atrial fibrillation or concomitant mitral valve disease were excluded. LAE was defined as indexed LA volume >34 ml/m² . The primary endpoint was cardiovascular dea

SUBMITTER: Asami M 

PROVIDER: S-EPMC9546325 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature