Does the Internal Carotid Artery Attenuate Blood-Flow Pulsatility in Small Vessel Disease? A 7 T 4D-Flow MRI Study.

ABSTRACT:

Background

Increased cerebral blood-flow pulsatility is associated with cerebral small vessel disease (cSVD). Reduced pulsatility attenuation over the internal carotid artery (ICA) could be a contributing factor to the development of cSVD and could be associated with intracranial ICA calcification (iICAC).

Purpose

To compare pulsatility, pulsatility attenuation, and distensibility along the ICA between patients with cSVD and controls and to assess the association between iICAC and pulsatility and distensibility.

Study type

Retrospective, explorative cross-sectional study.

Subjects

A total of 17 patients with cSVD, manifested as lacunar infarcts or deep intracerebral hemorrhage, and 17 age- and sex-matched controls.

Field strength/sequence

Three-dimension

SUBMITTER: van Tuijl RJ 

PROVIDER: S-EPMC9546379 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature