Predicting Kidney Failure, Cardiovascular Disease and Death in Advanced CKD Patients.

ABSTRACT:

Introduction

Predicting the timing and occurrence of kidney replacement therapy (KRT), cardiovascular events, and death among patients with advanced chronic kidney disease (CKD) is clinically useful and relevant. We aimed to externally validate a recently developed CKD G4+ risk calculator for these outcomes and to assess its potential clinical impact in guiding vascular access placement.

Methods

We included 1517 patients from the European Quality (EQUAL) study, a European multicentre prospective cohort study of nephrology-referred advanced CKD patients aged ≥65 years. Model performance was assessed based on discrimination and calibration. Potential clinical utility for timing of referral for vascular access placement was studied with diagnostic measures and decision curve an

SUBMITTER: Ramspek CL 

PROVIDER: S-EPMC9546766 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature