Estimating the impact of changes in weight and BMI on EQ-5D-3L: a longitudinal analysis of a behavioural group-based weight loss intervention.

ABSTRACT:

Purpose

To estimate the association between changes in BMI and changes in Health-Related Quality of Life (EQ-5D-3L).

Methods

The WRAP trial was a multicentre, randomised controlled trial with parallel design and recruited 1267 adults (BMI ≥ 28 kg/m²). Participants were allocated to Brief Intervention, a Commercial weight management Programme (WW, formerly Weight Watchers) for 12 weeks, or the same Programme for 52 weeks. Participants were assessed at 0, 3, 12, 24, and 60 months. We analysed the relationship between BMI and EQ-5D-3L, adjusting for age and comorbidities, using a fixed effects model. Test for attrition, model specification and missing data were conducted. Secondary analyses investigated a non-symmetric gradient for weight loss vs. regain.

Results<

SUBMITTER: Breeze P 

PROVIDER: S-EPMC9546944 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature