Prevalence and Characteristics of Carriage of Neisseria meningitidis Among Young Israeli Adults.

ABSTRACT:

Background

No updated data currently exist regarding Neisseria meningitidis carriage and genomic epidemiology among young Israeli adults.

Methods

Oropharyngeal swabs were collected from 1801 military recruits on the day of recruitment during 2019. Neisseria meningitidis was detected and identified by culture and quantitative polymerase chain reaction (qPCR). Confirmed isolates were serotyped by qPCR, and encapsulated strains underwent whole-genome sequencing. Risk factors for carriage were determined by analyzing focused questionnaires using uni- and multivariate models. Genomic typing was performed by means of core genome multilocus sequence typing.

Results

Carriage rates overall and of encapsulated strains were 20.1% and 6.7%, respectively. Genogroups

SUBMITTER: Sofer-Sali N 

PROVIDER: S-EPMC9547516 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature