Inflammatory plasma proteins predict short-term mortality in patients with an acute myocardial infarction.

ABSTRACT:

Background

The aim of this study was to investigate the association between inflammatory markers and 28-day mortality in patients with ST-elevation myocardial infarction (STEMI).

Methods

In 398 STEMI patients recorded between 2009 and 2013 by the population-based Myocardial Infarction Registry Augsburg, 92 protein biomarkers were measured in admission arterial blood samples using the OLINK inflammatory panel. In multivariable-adjusted logistic regression models, the association between each marker and 28-day mortality was investigated. The values of the biomarkers most significantly associated with mortality were standardized and summarized to obtain a prediction score for 28-day mortality. The predictive ability of this biomarker score was compared to the established GRACE

SUBMITTER: Schmitz T 

PROVIDER: S-EPMC9547640 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature