Antifungal activity of Taurolidine against Mucorales: An in vitro study on clinical isolates.

ABSTRACT:

Background and purpose

Taurolidine is active against a wide variety of micro-organisms, including bacteria and fungi. Mucormycosis is one of the life-threatening opportunistic fungal infections, especially in immunocompromised patients. Currently, the emergence of Mucormycosis during the COVID-19 pandemic raises public health concerns regarding untoward morbidity and mortality among SARS-CoV-2 patients. It is well-known that delayed and inappropriate antifungal therapy leads to increased morbidity and mortality. This study aimed to investigate the in-vitro antifungal activity of taurolidine to evaluate its effects against clinical isolates of Mucorales.

Materials and methods

This study included previously collected clinical Mucorales isolates. The minimu

SUBMITTER: Jafarian H 

PROVIDER: S-EPMC9548082 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature