Burden, clinical presentation and risk factors of advanced HIV disease in pregnant Mozambican women.

ABSTRACT:

Background

Information on the frequency and clinical features of advanced HIV disease (AHD) in pregnancy and its effects on maternal and perinatal outcomes is limited. The objective of this study was to describe the prevalence and clinical presentation of AHD in pregnancy, and to assess the impact of AHD in maternal and perinatal outcomes in Mozambican pregnant women.

Methods

This is a prospective and retrospective cohort study including HIV-infected pregnant women who attended the antenatal care (ANC) clinic at the Manhiça District Hospital between 2015 and 2020. Women were followed up for 36 months. Levels of CD4 + cell count were determined to assess AHD immune-suppressive changes. Risk factors for AHD were analyzed and the immune-suppressive changes over time and the eff

SUBMITTER: Nhampossa T 

PROVIDER: S-EPMC9548114 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature