Genome-wide association mapping reveals genes underlying population-level metabolome diversity in a fungal crop pathogen.

ABSTRACT:

Background

Fungi produce a wide range of specialized metabolites (SMs) involved in biotic interactions. Pathways for the production of SMs are often encoded in clusters of tightly arranged genes identified as biosynthetic gene clusters. Such gene clusters can undergo horizontal gene transfers between species and rapid evolutionary change within species. The acquisition, rearrangement, and deletion of gene clusters can generate significant metabolome diversity. However, the genetic basis underlying variation in SM production remains poorly understood.

Results

Here, we analyzed the metabolite production of a large population of the fungal pathogen of wheat, Zymoseptoria tritici. The pathogen causes major yield losses and shows variation in gene clusters. We performed untargete

SUBMITTER: Singh NK 

PROVIDER: S-EPMC9548119 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature