Two decades of FDG-PET/CT in seminoma: exploring its role in diagnosis, surveillance and follow-up.

ABSTRACT:

Background

Survivors of testicular cancer may experience long-term morbidity following treatment. There is an unmet need to investigate techniques that can differentiate individuals who need additional therapy from those who do not. 2-¹⁸fluoro-deoxy-D-glucose (FDG) positron emission tomography (PET) with computerised tomography (CT) may be helpful in select settings and may be used outside of current evidence-based recommendations in real-world practice.

Methods

A institutional FDG-PET/CT database of scans performed between 2000 and 2020 for adults with testicular seminoma was interrogated. Endpoints of interest included the positive (PPV) and negative (NPV) predictive value of FDG-PET/CT for identifying active seminoma (defined by progressive radiology, response

SUBMITTER: Conduit C 

PROVIDER: S-EPMC9548159 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature