Age-specific association between non-HDL-C and arterial stiffness in the Chinese population.

ABSTRACT:

Background

While some epidemiological studies have found correlations between non-high-density lipoprotein cholesterol (non-HDL-C) and arterial stiffness, there are still exist controversial and age-stratified analysis are scarce yet.

Methods

All individuals in this study were recruited in the Third Xiangya Hospital of Central South University from 2012 to 2016. Arterial stiffness was defined as brachial-ankle pulse wave velocity (baPWV) ≥1,400 cm/s. Association between non-HDL-C and arterial stiffness were explored using Cox proportional-hazards model. We also conducted subanalysis stratified by age. Furthermore, restricted cubic splines were used to model exposure-response relationships in cohort sample.

Results

This cohort study included 7,276 participants without

SUBMITTER: Wang J 

PROVIDER: S-EPMC9548648 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature