Leveraging genetic discoveries for sleep to determine causal relationships with common complex traits.

ABSTRACT: Sleep occurs universally and is a biological necessity for human functioning. The consequences of diminished sleep quality impact physical and physiological systems such as neurological, cardiovascular, and metabolic processes. In fact, people impacted by common complex diseases experience a wide range of sleep disturbances. It is challenging to uncover the underlying molecular mechanisms responsible for decreased sleep quality in many disease systems owing to the lack of suitable sleep biomarkers. However, the discovery of a genetic component to sleep patterns has opened a new opportunity to examine and understand the involvement of sleep in many disease states. It is now possible to use major genomic resources and technologies to uncover genetic contributions to many common diseases. Lar

SUBMITTER: Sonti S 

PROVIDER: S-EPMC9548675 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature