Bronchial hyperresponsiveness and asthma during oral immunotherapy for egg or peanut allergy in children.

ABSTRACT:

Background

Bronchial hyperresponsiveness (BHR) and asthma are frequently present in children with food allergy. We assessed BHR in children receiving oral immunotherapy (OIT) for persistent egg or peanut allergy and examined whether OIT affects asthma control.

Methods

Methacholine challenge testing was performed in 89 children with persistent egg or peanut allergy diagnosed by double-blind, placebo-controlled food challenge and 80 control children without food allergy. Of the 89 food-allergic children, 50 started OIT for egg allergy and 39 for peanut allergy. Sensitization to aeroallergens was evaluated by skin prick testing. Forty of the 89 children with regular controller treatment for asthma underwent methacholine challenge testing and 34 measurement of exhaled nitric oxi

SUBMITTER: Burman J 

PROVIDER: S-EPMC9549178 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature