Cardiac and vascular effects of low-dose steroids during the early phase of septic shock: An echocardiographic study.

ABSTRACT:

Background

Low-dose steroids are known to increase arterial pressure during septic shock through restoration of vasopressor response to norepinephrine. However, their effects on cardiac performance and ventriculo-arterial coupling (VAC) have never been scrutinized during human septic shock. The aim of this study was to perform a comprehensive description of the cardiovascular effects of low-dose steroids using modern echocardiographic tools (including speckle tracking imaging).

Methods

This prospective study was conducted in the intensive care unit (ICU) of a university hospital in France. Consecutive adult patients admitted for septic shock and requiring low-dose steroid therapy were prospectively enrolled within 24 h of septic shock onset. We recorded hemodynamic and echoc

SUBMITTER: Bagate F 

PROVIDER: S-EPMC9549363 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature