Serum creatinine to cystatin C ratio and clinical outcomes in adults with non-dialysis chronic kidney disease.

ABSTRACT:

Background

Studies have suggested that the serum creatinine/cystatin C (Cr/CysC) ratio is a surrogate marker for muscle wasting is associated with adverse outcomes in several disease conditions. To clarify the utility of the Cr/CysC ratio as a prognostic marker in chronic kidney disease (CKD) we evaluated the association between the Cr/CysC ratio clinical outcomes in patients with non-dialysis CKD.

Methods

This prospective observational cohort study included 1,966 participants of the KoreaN cohort study Outcomes in patients With CKD (KNOW-CKD). We evaluated associated factors with the serum Cr/CysC ratio and association between the serum Cr/CysC ratio and composite outcomes of all-cause death and cardiovascular events (CVEs).

Results

The mean age was 54 ± 12 (SD) year

SUBMITTER: Hyun YY 

PROVIDER: S-EPMC9550211 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature