Treatment and outcome of metastatic parathyroid carcinoma: A systematic review and pooled analysis of published cases.

ABSTRACT:

Background

Parathyroid carcinoma (PC) is an extremely rare malignant tumor with an incidence of about 6 new cases per 10 million inhabitants per year. While several papers have been published on treatments and outcomes of PC patients with loco-regional disease, little is known about the prognosis, treatment strategies, and prognostic factors of patients with distant metastasis.

Materials and methods

We performed a systematic review and a pooled analysis of histopathologically confirmed PC cases published in literature using the following keywords: "metastasis-metastatic-secondary nodes" AND "parathyroid carcinoma". Original case reports and case series reporting metastatic parathyroid carcinoma were included. Data from 58 articles were extracted in a piloted form by five rev

SUBMITTER: Alberti A 

PROVIDER: S-EPMC9550213 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature