Bridging cognition and action: executive functioning mediates the relationship between white matter fiber density and complex motor abilities in older adults.

ABSTRACT: Aging may be associated with motor decline that is attributed to deteriorating white matter microstructure of the corpus callosum (CC), among other brain-related factors. Similar to motor functioning, executive functioning (EF) typically declines during aging, with age-associated changes in EF likewise being linked to altered white matter connectivity in the CC. Given that both motor and executive functions rely on white matter connectivity via the CC, and that bimanual control is thought to rely on EF, the question arises whether EF can at least party account for the proposed link between CC-connectivity and motor control in older adults. To address this, diffusion magnetic resonance imaging data were obtained from 84 older adults. A fiber-specific approach was used to obtain fiber densit

SUBMITTER: Seer C 

PROVIDER: S-EPMC9550248 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature