Current Status of Phage Therapy against Infectious Diseases and Potential Application beyond Infectious Diseases.

ABSTRACT: Intestinal microbiota plays a key role in regulating the pathogenesis of human disease and maintaining health. Many diseases, mainly induced by bacteria, are on the rise due to the emergence of antibiotic-resistant strains. Intestinal microorganisms include organisms such as bacteria, viruses, and fungi. They play an important role in maintaining human health. Among these microorganisms, phages are the main members of intestinal viromes. In particular, the viral fraction, composed essentially of phages, affects homeostasis by exerting selective pressure on bacterial communities living in the intestinal tract. In recent years, with the widespread use and even abuse of antibacterial drugs, more and more drug-resistant bacteria have been found, and they show a trend of high drug resistance an

SUBMITTER: Xu HM 

PROVIDER: S-EPMC9550513 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature