No effect of nitrate-rich beetroot juice on microvascular function and blood pressure in younger and older individuals: a randomised, placebo-controlled double-blind pilot study.

ABSTRACT:

Background/objectives

To compare the effects of supplemental inorganic nitrate (NO₃) on microvascular endothelial function and blood pressure in younger vs. older participants.

Subjects/methods

25 individuals participated in a double-blind, randomised, placebo-controlled crossover pilot study. Participants were stratified by age (18-35 and ≥55 years) and consumed a single dose beetroot juice (providing 6.4 mmol NO₃) or NO₃-depleted beetroot juice. Blood pressure, microvascular function (via Laser Doppler Flowmetry; LDF) and urinary NO₃ were assessed, and the effects of NO₃ supplementation on cardiovascular parameters were compared between participants and conditions using mixed-design ANOVA.

Results

Treatments and

SUBMITTER: Rogerson D 

PROVIDER: S-EPMC9550618 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature