Association among prognostic nutritional index, post-operative infection and prognosis of stage II/III gastric cancer patients following radical gastrectomy.

ABSTRACT:

Background/objective

To investigate the influence of pre-operative immunological and nutritional status, assessed by the prognostic nutritional index (PNI) score, on post-operative infection, and the potential additive effects of low PNI and infection on prognosis after radical resection of stage II/III gastric cancer (GC).

Methods

The medical records of 2352 consecutive stage II/III GC patients who underwent radical gastrectomy were retrospectively reviewed. The independent predictors for infections were identified using univariate and multivariate analyses. Cox regression analysis was used to assess any associations between PNI, infection and OS.

Results

A total of 160 (6.8%) cases developed infections and low PNI (< 43.9) was confirmed as an independent predicto

SUBMITTER: Xiao Y 

PROVIDER: S-EPMC9550621 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature