Beyond pulmonary vein isolation for persistent atrial fibrillation: sequential high-resolution mapping to guide ablation.

ABSTRACT:

Purpose

We aimed to evaluate whether outcomes with ablation in persistent (PsAF) and long-standing persistent (LsPsAF) AF can be improved beyond what can be achieved with pulmonary vein isolation (PVI) alone, using individualized mapping to guide ablation.

Methods

We studied 20 pts (15 M, 68 ± 11y) with PsAF (14) or LsPsAF (6) referred for first-time AF ablation. Following antral PVI, individualized mapping (IM) was performed using a high-density mapping catheter stably and fully deployed for 30 s at each of 23 ± 9 sites per patient. Activation data were reviewed, and an ablation strategy designed to intersect areas of focal and rotational activity. Mean follow-up was 429 ± 131 days. The study population was compared to a matched contemporary control cohort (CC) of 20 consec

SUBMITTER: Malaczynska-Rajpold K 

PROVIDER: S-EPMC9550675 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature