A Research Domain Criteria (RDoC)-Guided Dashboard to Review Psilocybin Target Domains: A Systematic Review.

ABSTRACT:

Background

Preliminary results from randomized controlled studies as well as identified molecular, cellular, and circuit targets of select psychedelics (e.g., psilocybin) suggest that their effects are transdiagnostic. In this review, we exploit the Research Domain Criteria (RDoC) transdiagnostic framework, to synthesize extant literature on psilocybin.

Objective

We aimed to identify RDoC-based effects of psilocybin and vistas for future mechanistic and interventional research.

Methods

A systematic search in electronic databases (i.e., PubMed, Scopus, PsycINFO, and Web of Science) performed in January and February 2021 identified English articles published between 1990 and 2020 reporting the effects of psilocybin on mental health measures. Data from included articles

SUBMITTER: Pouyan N 

PROVIDER: S-EPMC9550777 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature