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Characterization of occult hepatitis B infection among Iranian liver transplant recipients.


ABSTRACT:

Background

The prevalence of occult hepatitis B infection (OBI) among Iranian liver transplant recipient patients has not been explored yet. The present study aimed to determine the OBI prevalence among Iranian liver transplant recipients.

Methods

This study encompassed 97 patients having undergone liver transplantation due to several clinical backgrounds in the Liver Transplantation Center, Tehran, Iran. After serological evaluation, two different types of PCR methods were applied for amplification of HBV DNA, followed by the direct sequencing of whole hepatitis B virus (HBV) surface genes.

Results

At the time of admission, none of the patients were positive for HBsAg. However, 24 (25%), 12 (12.3%), and 5 (5.1%) cases were positive for anti-HBc, hepatitis C virus (HC

SUBMITTER: Khamseh A 

PROVIDER: S-EPMC9551123 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature