A Task-Specific Algorithm to Estimate Occupational (1→3)-β-D-glucan Exposure for Farmers in the Biomarkers of Exposure and Effect in Agriculture Study.

ABSTRACT:

Objectives

Farmers may be exposed to glucans (a cell component of molds) through a variety of tasks. The magnitude of exposure depends on each farmer's activities and their duration. We developed a task-specific algorithm to estimate glucan exposure that combines measurements of (1→3)-β-D-glucan with questionnaire responses from farmers in the Biomarkers of Exposure and Effect in Agriculture (BEEA) study.

Methods

To develop the algorithm, we first derived task-based geometric means (GMs) of glucan exposure for farming tasks using inhalable personal air sampling data from a prior air monitoring study in a subset of 32 BEEA farmers. Next, these task-specific GMs were multiplied by subject-reported activity frequencies for three time windows (the past 30 days, past 7 days, and

SUBMITTER: Friesen MC 

PROVIDER: S-EPMC9551320 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature